Best Answer: I would recommend not taking them together. Zyrtec is an over-the-counter allergy medication. Look for Zyrtec coupons for allergy medicine between $2.00 and $5.00 off, with some as high as $10.00 off. Advil (ibuprofen) is a non-steroidal anti-inflammatory which must be taken every 6. Xyzal Singular (morning) My conclusion regarding Zyrtec vs. It didn't make me feel groggy in the morning. For the Zyrtec worked better. I find that I feel best when I take a single pill of Allegra-D in the morning and a single pill of Zyrtec at night. Zyrtec doesn't have ibuprofen in it Ibuprofen is an anti-inflammatory and fever-reducing medication. The only side effect that seems to be worse for me levitra diabetes than with a single tablet is the dry mouth and mild dehydration.